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| Nomenclature |
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Symbol:
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Tlx2tm1Htno
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Name:
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T cell leukemia, homeobox 2;
targeted mutation 1, Masahiko Hatano
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MGI ID: |
MGI:2448951 |
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Synonyms: |
Ncx-/- |
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Gene:
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Tlx2
Location:
Chr6:83068317-83070293 bp, - strand
Genetic Position: Chr6,
35.94 cM, cytoband C3-D1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:42356
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The gene was disrupted by replacement of a 0.9kb fragment containing the 5' upstream region and part of exon 1 with a neomycin resistance cassette via homologous recombination. (J:42356)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tlx2 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:42356
Hatano M et al.,
"A novel pathogenesis of megacolon in Ncx/Hox11L.1 deficient mice."
J Clin Invest 1997 Aug 15;100(4):795-801
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All: |
1 reference(s)
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Analysis Tools
