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| Nomenclature |
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Symbol:
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Tg(Gfap-cre)1Sbk
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Name:
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transgene insertion 1, Suzanne Baker
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MGI ID: |
MGI:2448664 |
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Synonyms: |
(gfap)-cre, Gfap-cre |
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Transgene:
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Tg(Gfap-cre)1Sbk
Location:
unknown
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Transgene origin |
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Strain of Origin:
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Not Specified
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Transgene description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses Cre recombinase under the control of a modified glial fibrillary acidic protein. This promoter drives expression in the majority of the granule neurons of the cerebellum and dentate gyrus. (J:75499)
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Recombinase activity
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Driver:
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Gfap
Summary of all recombinase alleles
driven by Gfap.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
Phenotypic Similarity to Human Syndrome: Cortical Dysplasia (Ptentm2Mak/Ptentm2Mak Tg(Gfap-cre)1Sbk mice, J:149829)
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| References |
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Original: |
J:75499
Kwon CH et al.,
"Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease."
Nat Genet 2001 Dec;29(4):404-11
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All: |
7 reference(s)
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