Mnx1tm4(cre)Tmj
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Mnx1tm4(cre)Tmj
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Name:
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motor neuron and pancreas homeobox 1;
targeted mutation 4, Thomas M Jessell
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MGI ID: |
MGI:2447793 |
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Synonyms: |
Hb9-CRE, HB9cre, HB9Cre, Hlxb9tm4(cre)Tmj |
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Gene:
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Mnx1
Location:
Chr5:29473038-29478519 bp, - strand
Genetic Position: Chr5,
15.04 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:69623
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: Exon 1 was disrupted by the insertion of a cassette containing an IRES-tau-cre gene, a floxed neomycin gene, and a SV40 polyadenylation signal. (J:69623)
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Recombinase activity
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Activity in:
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alimentary system,
cardiovascular system,
embryo-other,
endocrine system,
hemolymphoid system,
integumental system,
limbs,
muscle,
nervous system,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs
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Not detected in:
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adipose tissue,
branchial arches,
liver & biliary system,
mesenchyme,
skeletal system,
tail
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Driver:
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Mnx1
Summary of all recombinase alleles
driven by Mnx1.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:69623
Yang X et al.,
"Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation."
Neuron 2001 May;30(2):399-410
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All: |
30 reference(s)
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Analysis Tools
