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Nrg1tm3Cbm
Targeted Allele Detail

Nomenclature
Symbol: Nrg1tm3Cbm
Name: neuregulin 1; targeted mutation 3, Carmen Birchmeier
MGI ID: MGI:2447761
Synonyms: nrg-1f, nrg-1flox
Gene: Nrg1   Location: Chr8:31818028-31918203 bp, - strand    Genetic Position: Chr8, 18.75 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:69623
Parent Cell Line: E14.1 (ES Cell)
Strain of Origin: 129P2/OlaHsd
Mutation
description
Allele Type:   Targeted (Floxed/Frt)
Mutation:   Insertion
    A floxed allele was generated that contained loxP sites inserted into intron 6 and in intron 9. (J:69623)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nrg1 Mutation: 5 strains or lines available
References
Original: J:69623 Yang X et al., "Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation." Neuron 2001 May;30(2):399-410
All: 8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/05/2013
MGI 5.13
The Jackson Laboratory