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| Nomenclature |
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Symbol:
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Isl1tm1(cre)Tmj
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Name:
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ISL1 transcription factor, LIM/homeodomain;
targeted mutation 1, Thomas M Jessell
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MGI ID: |
MGI:2447758 |
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Synonyms: |
Isl1cre, Isl1-Cre, Isl1-IRES-Cre, Isl1tm1(cre)Cos, Isl-Cre, Islet1:Cre |
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Gene:
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Isl1
Location:
Chr13:116298281-116309688 bp, - strand
Genetic Position: Chr13,
64.87 cM, cytoband D2.3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:80963
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Parent Cell Line:
| JM-1 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: An IRES-Cre-SV40pA cassette was inserted into the exon encoding the second LIM domain of Isl1. Endogenous regulatory sequences drive Cre expression in motor neurons and dorsal root and cranial sensory ganglia. (J:80963)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:80963
Srinivas S et al.,
"Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus."
BMC Dev Biol 2001;1(1):4
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All: |
36 reference(s)
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Analysis Tools
