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| Nomenclature |
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Symbol:
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Il3tm1Glli
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Name:
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interleukin 3;
targeted mutation 1, Stephen J Galli
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MGI ID: |
MGI:2446538 |
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Synonyms: |
Il-3- |
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Gene:
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Il3
Location:
Chr11:54265303-54267277 bp, - strand
Genetic Position: Chr11,
32.13 cM, cytoband B1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:80640
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 5' portion of exon 3 was replaced by the insertion of a neomycin selection cassette. The absence of normal protein was indicated by ELISA and proliferative studies using a myeloid cell line. (J:80640)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:80640
Mach N et al.,
"Involvement of interleukin-3 in delayed-type hypersensitivity."
Blood 1998 Feb 1;91(3):778-83
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All: |
17 reference(s)
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Analysis Tools
