|
|
| Nomenclature |
|
Symbol:
|
Tg(Eno2-Hgf)1Tnak
|
|
Name:
|
transgene insertion 1, Toshikazu Nakamura
|
|
MGI ID: |
MGI:2446529 |
|
Synonyms: |
NSE-HGF-Tg |
|
Transgene:
|
Tg(Eno2-Hgf)1Tnak
Location:
unknown
|
|
Transgene origin |
|
Strain of Origin:
|
C57BL/6
|
|
Transgene description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The full length rat hepatocyte growth factor (Hgf) cDNA was tagged with the KT3 epitope,followed by a polyadenylation signal, and inserted downstream of the neuron specific Eno2 promoter. RNAse protection showed expression of the Hgf transgene in the brain and spinal cord. (J:78090, J:128738)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:78090
Sun W et al.,
"Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS."
J Neurosci 2002 Aug 1;22(15):6537-48
|
|
All: |
5 reference(s)
|
|