En1tm2(cre)Wrst
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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En1tm2(cre)Wrst
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Name:
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engrailed 1;
targeted mutation 2, Wolfgang Wurst
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MGI ID: |
MGI:2446434 |
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Synonyms: |
En1Cki, En1Cre, En1-Cre, En1tm6(cre)Alj |
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Gene:
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En1
Location:
Chr1:120602418-120609296 bp, + strand
Genetic Position: Chr1,
52.74 cM, cytoband C2-qter
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:62572
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A cre recombinase gene cassette was inserted into the En1 locus. A loxP flanked neomycin cassette is removed in vivo via a Cre-mediated recombination event. (J:62572)
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Recombinase activity
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Activity in:
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adipose tissue,
alimentary system,
branchial arches,
cavities & their linings,
integumental system,
limbs,
mesenchyme,
muscle,
nervous system,
postnatal-other,
reproductive system,
sensory organs,
skeletal system,
tail
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Not detected in:
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cardiovascular system,
embryo-other,
endocrine system,
hemolymphoid system,
liver & biliary system,
renal & urinary system,
respiratory system
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Driver:
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En1
Summary of all recombinase alleles
driven by En1.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:62572
Kimmel RA et al.,
"Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation."
Genes Dev 2000 Jun 1;14(11):1377-89
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All: |
62 reference(s)
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Analysis Tools
