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| Nomenclature |
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Symbol:
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Juntm4Wag
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Name:
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Jun oncogene;
targeted mutation 4, Erwin F Wagner
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MGI ID: |
MGI:2445420 |
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Synonyms: |
c-junf, junf |
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Gene:
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Jun
Location:
Chr4:95049034-95052222 bp, - strand
Genetic Position: Chr4,
43.34 cM, cytoband C5-C7
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:75863
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: The gene was flanked with a loxP site and a floxed neo-TK cassette via homologous recombination. The neo-TK cassette was removed in correctly targeted ES cells by transient expression of cre recombinase. The resulting mutation consists of Jun flanked by single loxP sites. (J:75863)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Jun Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:75863
Behrens A et al.,
"Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver."
EMBO J 2002 Apr 2;21(7):1782-90
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All: |
33 reference(s)
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Analysis Tools
