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| Nomenclature |
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Symbol:
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Tg(RIP1-Tag)2Dh
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Name:
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transgene insertion 2, Douglas Hanahan
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MGI ID: |
MGI:2429941 |
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Synonyms: |
Rip1Tag2, RIP1-Tag2, RIP-Tag2, RT2 |
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Transgene:
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Tg(RIP1-Tag)2Dh
Location:
unknown
Genetic Position: Chr2,
Syntenic
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Transgene
origin |
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Strain of Origin:
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(C57BL/6J x DBA/2J)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: 695 bp of 5' flanking DNA from the rat insulin promoter was used to drive expression of large T antigen in pancreatic beta cells. (J:50695)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Four transgenic lines were produced. Transgenic mice die prematurely at 9-12 weeks of age.
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| References |
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Original: |
J:50695
Hanahan D,
"Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes."
Nature 1985 May 9-15;315(6015):115-22
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All: |
110 reference(s)
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Analysis Tools
