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| Nomenclature |
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Symbol:
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Cd200tm1Jods
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Name:
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CD200 antigen;
targeted mutation 1, Jonathon D Sedgwick
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MGI ID: |
MGI:2429651 |
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Synonyms: |
CD200- |
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Gene:
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Cd200
Location:
Chr16:45382135-45409053 bp, - strand
Genetic Position: Chr16,
29.53 cM, cytoband A1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:65982
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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C57BL/6
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A portion of exon 3 was replaced by a neomycin selection cassette. Protein expression was examined by immunohistochemical and flow cytometric analyses and determined to be absent in the CNS, B cells, follicular dendritic cells, and splenic endothelium of homozygous mutant mice. (J:65982)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cd200 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:65982
Hoek RM et al.,
"Down-regulation of the macrophage lineage through interaction with OX2 (CD200)"
Science 2000 Dec 1;290(5497):1768-71
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All: |
12 reference(s)
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Analysis Tools
