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| Nomenclature |
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Symbol:
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Sox9tm2Crm
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Name:
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SRY-box containing gene 9;
targeted mutation 2, Benoit de Crombrugghe
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MGI ID: |
MGI:2429649 |
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Synonyms: |
Sox9flox, Sox9loxP |
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Gene:
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Sox9
Location:
Chr11:112782224-112787760 bp, + strand
Genetic Position: Chr11,
77.27 cM
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Skeletal image of newborn Sox9tm2Crm/Sox9tm2Crm Tg(Wnt1-cre)11Rth/0 mice
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:79879
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A neomycin resistance gene was inserted downstream of exon 3 and loxP sites flanking exon 2 and neo were introduced. (J:79879)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:79879
Akiyama H et al.,
"The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6."
Genes Dev 2002 Nov 1;16(21):2813-28
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All: |
31 reference(s)
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Analysis Tools
