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| Nomenclature |
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Symbol:
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Tg(Hsp70-1-cre)6Arge
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Name:
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transgene insertion 6, Argiris Efstratiadis
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MGI ID: |
MGI:2389573 |
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Synonyms: |
Hs-cre6, Hspa1b-cre6 |
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Transgene:
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Tg(Hsp70-1-cre)6Arge
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6J x CBA
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: A sequence fragment from the murine Hsp70-1 locus encompassing 655 bp of the 5' flanking and noncoding sequence was adjoined to sequence encoding cre recombinase. A single integration of the transgenic construct was identified in the founder line. Graded expression of the transgenic construct (determined by a range of 0% to 100% recombination of reporter loci) was observed in non heat shock induced embryos. Additionally, heat shock induces expression. (J:60711)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:60711
Dietrich P et al.,
"Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes."
Mamm Genome 2000 Mar;11(3):196-205
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All: |
7 reference(s)
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Analysis Tools
