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| Nomenclature |
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Symbol:
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Gdi1tm1Toni
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Name:
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guanosine diphosphate (GDP) dissociation inhibitor 1;
targeted mutation 1, Daniela Toniolo
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MGI ID: |
MGI:2388605 |
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Gene:
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Gdi1
Location:
ChrX:74304998-74311862 bp, + strand
Genetic Position: ChrX,
37.97 cM, cytoband B-C1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:79454
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The coding regions of exons 1 through 4 were replaced by a cassette containing lacZ followed by a floxed neo. Protein was undetected by Western blot analysis of brain tissue obtained from male hemizygous mice. (J:79454)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gdi1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:79454
D'Adamo P et al.,
"Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice."
Hum Mol Genet 2002 Oct 1;11(21):2567-80
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All: |
2 reference(s)
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Analysis Tools
