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| Nomenclature |
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Symbol:
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Cnga3tm1Biel
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Name:
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cyclic nucleotide gated channel alpha 3;
targeted mutation 1, Martin Biel
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MGI ID: |
MGI:2388388 |
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Synonyms: |
CNG3- |
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Gene:
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Cnga3
Location:
Chr1:37218336-37263384 bp, + strand
Genetic Position: Chr1,
15.46 cM, cytoband B
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Retinal morphology of 2 month old Cnga3tm1Biel/Cnga3tm1Biel and wild-type mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:56020
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The gene was disrupted by replacement of exon 7 with a neomycin resistance cassette. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of retina RNA. (J:56020)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cnga3 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:56020
Biel M et al.,
"Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3."
Proc Natl Acad Sci U S A 1999 Jun 22;96(13):7553-7
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All: |
23 reference(s)
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Analysis Tools
