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| Nomenclature |
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Symbol:
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Pde6brd10
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Name:
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phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide;
retinal degeneration 10
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MGI ID: |
MGI:2388259 |
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Synonyms: |
Pde6brd1-J, rd10 |
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Gene:
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Pde6b
Location:
Chr5:108388391-108432397 bp, + strand
Genetic Position: Chr5,
53.07 cM
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Mutation
origin |
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Strain of Origin:
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CXB1/ByJ
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Nucleotide substitutions |
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Mutation details: An initial complementation test with Pde6b rd1 demonstrated allelism. Sequence analysis shows that the rd10 mutation is caused by a missense mutation in exon 13, which encodes the beta subunit of the protein.
(J:75095)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:75095
Chang B et al.,
"Retinal degeneration mutants in the mouse."
Vision Res 2002 Feb;42(4):517-25
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All: |
29 reference(s)
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Analysis Tools
