|
|
| Nomenclature |
|
Symbol:
|
Gpr132tm1Witt
|
|
Name:
|
G protein-coupled receptor 132;
targeted mutation 1, Owen N Witte
|
|
MGI ID: |
MGI:2388138 |
|
Synonyms: |
G2A- |
|
Gene:
|
Gpr132
Location:
Chr12:112850876-112860916 bp, - strand
Genetic Position: Chr12,
61.25 cM, cytoband F2
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:69473
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129X1/SvJ
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: The gene was disrupted by replacement of exon 2 (98% of the total coding sequence) with an IRES-lacZ-PGK-neo cassette. Absence of gene expression was confirmed by RT-PCR analysis of pre-B and -T cells from homozygous mutant animals. (J:69473)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:69473
Le LQ et al.,
"Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome."
Immunity 2001 May;14(5):561-71
|
|
All: |
8 reference(s)
|
|
Analysis Tools
