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| Nomenclature |
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Symbol:
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Adipoqtm1Chan
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Name:
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adiponectin, C1Q and collagen domain containing;
targeted mutation 1, Lawrence Chan
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MGI ID: |
MGI:2388007 |
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Synonyms: |
Ad-, Adipo-, ADN- |
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Gene:
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Adipoq
Location:
Chr16:23146536-23158028 bp, + strand
Genetic Position: Chr16,
13.96 cM, cytoband B3-B4
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:79122
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 was replaced by a floxed neo cassette inserted by homologous recombination. Transcript was undetected in adipose tissue by Northern blot analysis of homozygous mutant mice. The lack of immunoreactivity by Western blot analysis using a carboxy terminal antibody indicated an absence of normal and truncated protein. (J:79122)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:79122
Ma K et al.,
"Increased beta -oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin."
J Biol Chem 2002 Sep 20;277(38):34658-61
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All: |
26 reference(s)
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Analysis Tools
