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| Nomenclature |
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Symbol:
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Hey2tm1Uts
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Name:
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hairy/enhancer-of-split related with YRPW motif 2;
targeted mutation 1, Manuel F Utset
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MGI ID: |
MGI:2387940 |
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Synonyms: |
Hey2lacZ |
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Gene:
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Hey2
Location:
Chr10:30832359-30842801 bp, - strand
Genetic Position: Chr10,
17.19 cM, cytoband A4
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:79025
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A genomic fragment, extending from codon 19 in exon 1 through a portion of exon 3, was replaced with a cassette containing lacZ and neo. The deleted region encoded the basic helix-loop-helix, Orange, and YXXW domains. The expression pattern of the fusion protein containing lacZ was similar to that of the endogenous pattern. (J:79025)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hey2 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:79025
Donovan J et al.,
"Tetralogy of fallot and other congenital heart defects in hey2 mutant mice."
Curr Biol 2002 Sep 17;12(18):1605
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All: |
1 reference(s)
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Analysis Tools
