|
|
| Nomenclature |
|
Symbol:
|
Ogttm1Gwh
|
|
Name:
|
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase);
targeted mutation 1, Gerald W Hart
|
|
MGI ID: |
MGI:2387867 |
|
Synonyms: |
OGTF |
|
Gene:
|
Ogt
Location:
ChrX:101640060-101684351 bp, + strand
Genetic Position: ChrX,
44.45 cM, cytoband D
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:62279
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The exon encoding amino acids 206 through 232 (numbering derived from the rat cDNA encoding 1037 residues) was flanked by single loxP sites. (J:62279)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:62279
Shafi R et al.,
"The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny."
Proc Natl Acad Sci U S A 2000 May 23;97(11):5735-9
|
|
All: |
3 reference(s)
|
|