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| Nomenclature |
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Symbol:
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Ptf1atm1(cre)Cvw
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Name:
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pancreas specific transcription factor, 1a;
targeted mutation 1, Christopher VE Wright
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MGI ID: |
MGI:2387804 |
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Gene:
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Ptf1a
Location:
Chr2:19445663-19447501 bp, + strand
Genetic Position: Chr2,
13.37 cM, cytoband A2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:78710
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The entire coding region was replaced with a cassette containing cre recombinase and a floxed neomycin resistance gene by RMCE using Ptf1atm1Mgn. (J:78710)
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Recombinase activity
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Driver:
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Ptf1a
Summary of all recombinase alleles
driven by Ptf1a.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ptf1a Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:78710
Kawaguchi Y et al.,
"The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors."
Nat Genet 2002 Sep;32(1):128-34
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All: |
6 reference(s)
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Analysis Tools
