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| Nomenclature |
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Symbol:
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Zeb2tm1.2Yhi
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Name:
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zinc finger E-box binding homeobox 2;
targeted mutation 1.2, Yujiro Higashi
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MGI ID: |
MGI:2387501 |
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Synonyms: |
SIP1delta ex7, Zfhx1bdeltaex7 |
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Gene:
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Zeb2
Location:
Chr2:44983732-45117395 bp, - strand
Genetic Position: Chr2,
27.31 cM, cytoband C1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:75138
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exon 7, which encodes the fourth zinc finger of the amino terminal zinc finger cluster, the Madh binding domain, the homeodomain like sequence, and the CtBP binding sites, were deleted along with a floxed neo cassette by in vivo cre recombination of Zhx1btm1Yhi. The absence of protein was confirmed by Western blot analysis of homozygous mutant mice. (J:75138)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:75138
Higashi Y et al.,
"Generation of the floxed allele of the SIP1 (Smad-interacting protein 1) gene for Cre-mediated conditional knockout in the mouse."
Genesis 2002 Feb;32(2):82-4
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All: |
7 reference(s)
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Analysis Tools
