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| Nomenclature |
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Symbol:
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Cd79btm1Mnz
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Name:
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CD79B antigen;
targeted mutation 1, Michel C Nussenzweig
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MGI ID: |
MGI:2387024 |
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Synonyms: |
Igbeta- |
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Gene:
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Cd79b
Location:
Chr11:106311341-106314762 bp, - strand
Genetic Position: Chr11,
68.89 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:79045
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The gene was disrupted by replacement of the promoter, exon 1, and part of exon 2 with a neomycin resistance cassette. Northern blot of bone marrow RNA from homozygous mutant animals confirmed the absence of gene expression. (J:79045)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cd79b Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:79045
Gong S et al.,
"Regulation of an early developmental checkpoint in the B cell pathway by Ig beta."
Science 1996 Apr 19;272(5260):411-4
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All: |
4 reference(s)
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Analysis Tools
