|
|
| Nomenclature |
|
Symbol:
|
Hbb-artm1.1Mkg
|
|
Name:
|
hemoglobin, activating region;
targeted mutation 1.1, Mark Groudine
|
|
MGI ID: |
MGI:2386946 |
|
Synonyms: |
deltaLCR |
|
Gene:
|
Hbb-ar
Location:
unknown
Genetic Position: Chr7,
Syntenic
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:60714
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Deletion |
| |
|
Mutation details: This allele is derived from Hbb-artm1Mgk. The 24 kb region of the gene containing 5' HS sites 1-6 flanked by loxP sites were removed by mating mutant animals to a cre-expressing line. Correct removal of the floxed sites was confirmed by Southern blot analysis. (J:60714)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Hbb-ar Mutation:
|
0 strains or lines available |
|
| References |
|
Original: |
J:60714
Bender MA et al.,
"Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region."
Mol Cell 2000 Feb;5(2):387-93
|
|
All: |
5 reference(s)
|
|
Analysis Tools
