|
|
| Nomenclature |
|
Symbol:
|
Tg(Cd4-cre)1Cwi
|
|
Name:
|
transgene insertion 1, Christopher B Wilson
|
|
MGI ID: |
MGI:2386448 |
|
Synonyms: |
CD4cre, CD4-Cre, CD4-Cre+, CD4-creTg, CD4p-Cre |
|
Transgene:
|
Tg(Cd4-cre)1Cwi
Location:
unknown
|
|
Transgene
origin |
|
Strain of Origin:
|
(C57BL/6 x DBA/2)F2
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (Cre/Flp) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: Cre recombinase is expressed under the control of mouse Cd4 regulatory elements. The Cd4 enhancer, promoter and silencer collectively drive expression at sequential stages specifically of CD4+ T cell development. (J:73127)
|
|
|
Recombinase activity
|
|
Driver:
|
Cd4
Summary of all recombinase alleles
driven by Cd4.
|
|
MGI has not yet included tissue activity data for this allele in any anatomical systems.
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:73127
Lee PP et al.,
"A critical role for dnmt1 and DNA methylation in T cell development, function, and survival."
Immunity 2001 Nov;15(5):763-74
|
|
All: |
316 reference(s)
|
|
Analysis Tools
