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| Nomenclature |
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Symbol:
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Smad4tm2.1Cxd
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Name:
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SMAD family member 4;
targeted mutation 2.1, Chu-Xia Deng
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MGI ID: |
MGI:2386393 |
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Synonyms: |
Smad4Co, Smad4fl, Smad4flox, Smad4fx(exon8), Smad4loxp, Smadflox |
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Gene:
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Smad4
Location:
Chr18:73639009-73703780 bp, - strand
Genetic Position: Chr18,
49.51 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:75140
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 8 was left flanked by single loxP sites after the floxed neo cassette was excised by the in vivo expression of cre recombinase. (J:75140)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:75140
Yang X et al.,
"Generation of Smad4/Dpc4 conditional knockout mice."
Genesis 2002 Feb;32(2):80-1
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All: |
80 reference(s)
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Analysis Tools
