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| Nomenclature |
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Symbol:
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Itga9tm1Des
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Name:
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integrin alpha 9;
targeted mutation 1, Dean Sheppard
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MGI ID: |
MGI:2386308 |
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Synonyms: |
alpha9- |
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Gene:
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Itga9
Location:
Chr9:118606690-118901003 bp, + strand
Genetic Position: Chr9,
70.32 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:63038
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Parent Cell Line:
| RF8 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette into exon 1 via homologous recombination. RT-PCR and Western blot analyses performed on liver homogenates from homozygous mutant animals did not detect gene transcripts or protein product. (J:63038)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Itga9 Mutation:
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8 strains or lines available |
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| References |
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Original: |
J:63038
Huang XZ et al.,
"Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1."
Mol Cell Biol 2000 Jul;20(14):5208-15
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All: |
5 reference(s)
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Analysis Tools
