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| Nomenclature |
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Symbol:
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Pigatm1Tak
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Name:
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phosphatidylinositol glycan anchor biosynthesis, class A;
targeted mutation 1, Junji Takeda
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MGI ID: |
MGI:2386120 |
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Synonyms: |
Pig-aflox |
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Gene:
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Piga
Location:
ChrX:164419793-164433916 bp, + strand
Genetic Position: ChrX,
76.49 cM, cytoband F3-F4
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Epidermal morphology of wild type and Pigatm1Tak/Y Tg(KRT5-cre)1Tak mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:41746
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 6 was left flanked by loxP sites after the in vitro expression of cre recombinase. The potential for cre-mediated recombination was demonstrated in ES cells. (J:41746)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Piga Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:41746
Tarutani M et al.,
"Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development."
Proc Natl Acad Sci U S A 1997 Jul 8;94(14):7400-5
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All: |
12 reference(s)
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Analysis Tools
