|
|
| Nomenclature |
|
Symbol:
|
Tg(Pbsn-cre)4Prb
|
|
Name:
|
transgene insertion 4, Pradip Roy-Burman
|
|
MGI ID: |
MGI:2385927 |
|
Synonyms: |
ARR2PB-Cre, PB-Cre, PbCre4, PB-Cre4 |
|
Transgene:
|
Tg(Pbsn-cre)4Prb
Location:
unknown
|
|
Show the 1 image(s) involving this allele.
|
|
Transgene
origin |
|
Strain of Origin:
|
(C57BL/6 x DBA/2)F1
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (Cre/Flp) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The transgene is composed of the cre recombinase gene under the control of a composite promoter derived from rat Pbsn. The rat Pbsn promoter drives postnatal transgene expression in the prostatic epithelium. The transgene is expressed postnatally in prostatic epithelium with the highest level of expression in the lateral lobe of the prostate gland. A very low level of transgene expression was detected in the seminal vesicles, testes, and ovaries. No transgeneexpression was detected in any of the other tissue types examined. (J:68167)
|
|
|
Recombinase activity
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:68167
Wu X et al.,
"Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation."
Mech Dev 2001 Mar;101(1-2):61-9
|
|
All: |
73 reference(s)
|
|
Analysis Tools
