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| Nomenclature |
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Symbol:
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Sox9tm1.1Gsr
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Name:
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SRY-box containing gene 9;
targeted mutation 1.1, Gerd Scherer
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MGI ID: |
MGI:2385469 |
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Synonyms: |
Sox9-delex2,3 |
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Gene:
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Sox9
Location:
Chr11:112782224-112787760 bp, + strand
Genetic Position: Chr11,
77.27 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:75124
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The floxed region containing exons 2 and 3 was excised from Sox9tm1Gsr via in vivo expression of cre recombinase. The deleted region encoded a portion of the DNA-binding high mobility group domain and the entire transactivation domain. (J:75124)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sox9 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:75124
Kist R et al.,
"Conditional inactivation of Sox9: a mouse model for campomelic dysplasia."
Genesis 2002 Feb;32(2):121-3
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All: |
2 reference(s)
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Analysis Tools
