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| Nomenclature |
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Symbol:
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Cited2tm1Ycy
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Name:
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Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2;
targeted mutation 1, Yu-Chung Yang
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MGI ID: |
MGI:2385355 |
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Synonyms: |
Cited2- |
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Gene:
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Cited2
Location:
Chr10:17723228-17725673 bp, + strand
Genetic Position: Chr10,
7.18 cM, cytoband A2
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Eye phenotype and exencephaly of Cited2tm1Ycy/Cited2tm1Ycy mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:78364
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The entire coding region of the endogenous gene was replaced by a neomycin selection cassette. Transcript was undetected in by Northern blot analysis of total embryonic RNA. (J:78364)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cited2 Mutation:
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9 strains or lines available |
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Notes |
ES cell line = R19.
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| References |
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Original: |
J:78364
Yin Z et al.,
"The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation."
Proc Natl Acad Sci U S A 2002 Aug 6;99(16):10488-93
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All: |
7 reference(s)
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Analysis Tools
