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| Nomenclature |
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Symbol:
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Frat1tm1Brn
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Name:
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frequently rearranged in advanced T cell lymphomas;
targeted mutation 1, Anton Berns
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MGI ID: |
MGI:2384128 |
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Synonyms: |
Frat1-, Frat1lacZ |
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Gene:
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Frat1
Location:
Chr19:41830168-41830809 bp, + strand
Genetic Position: Chr19,
35.3 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:58550
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: 660 nucleotides of the coding region were replaced with a cassette containing a lacZ beta-galactosidase gene and hygromycin selection gene. Expression of lacZ was driven by the endogenous promoter. Northern blot analysis confirmed the absence of transcript produced from the targeted locus. (J:58550)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Expression |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:58550
Jonkers J et al.,
"In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3."
Mech Dev 1999 Nov;88(2):183-94
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All: |
3 reference(s)
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Analysis Tools
