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Pafah1b1tm1Awb
Targeted Allele Detail

Nomenclature
Symbol: Pafah1b1tm1Awb
Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; targeted mutation 1, Anthony Wynshaw-Boris
MGI ID: MGI:2384054
Synonyms: Lis1-, Lis-Neo, Pafah1b1ex6neo-8, Pafah1b1-neo
Gene: Pafah1b1   Location: Chr11:74673949-74724670 bp, - strand    Genetic Position: Chr11, 45.76 cM, cytoband B3
Disruption of hippocampal layers in Lrp8tm1Her/Lrp8tm1Her, Pafah1b1tm1Awb/Pafah1b1+, and Lrp8tm1Her/Lrp8tm1Her Pafah1b1tm1Awb/Pafah1b1+ mice

Show the 3 image(s) involving this allele.

Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:49531
Parent Cell Line: TC1/TC-1 (ES Cell)
Strain of Origin: 129S6/SvEvTac
Mutation
description
Allele Type:   Targeted (knock-out)
Mutation:   Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pafah1b1 Mutation: 147 strains or lines available
References
Original: J:49531 Hirotsune S et al., "Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality [see comments]" Nat Genet 1998 Aug;19(4):333-9
All: 29 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory