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| Nomenclature |
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Symbol:
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Rad52tm1Aps
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Name:
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RAD52 homolog (S. cerevisiae);
targeted mutation 1, Albert Pastink
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MGI ID: |
MGI:2383953 |
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Synonyms: |
MmRAD52- |
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Gene:
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Rad52
Location:
Chr6:119902698-119922828 bp, + strand
Genetic Position: Chr6,
56.86 cM, cytoband G3
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:50357
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Parent Cell Line:
| IB10/E14IB10 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 3 was replaced with a neomycin selection cassette. Western blot analysis of homozygous mutant ES cells showed an absence of both normal and truncated protein. (J:50357)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:50357
Rijkers T et al.,
"Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation."
Mol Cell Biol 1998 Nov;18(11):6423-9
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All: |
4 reference(s)
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