|
|
| Nomenclature |
|
Symbol:
|
Gcdhtm1Dmk
|
|
Name:
|
glutaryl-Coenzyme A dehydrogenase;
targeted mutation 1, David M Koeller
|
|
MGI ID: |
MGI:2182942 |
|
Synonyms: |
Gcdh- |
|
Gene:
|
Gcdh
Location:
Chr8:84886393-84893921 bp, - strand
Genetic Position: Chr8,
41.28 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:77874
|
|
Parent Cell Line:
| J1 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJae
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: Coding sequences in exon 1 were fused in-frame to a lacZ gene followed by a neomycin resistance cassette, which also replaced the 3' end of exon 1 through exon 7. A beta-galactosidase protein was expressed from this allele under the control of the endogenous promoter. (J:77874)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:77874
Koeller DM et al.,
"Biochemical, pathologic and behavioral analysis of a mouse model of glutaric acidemia type I."
Hum Mol Genet 2002 Feb 15;11(4):347-57
|
|
All: |
10 reference(s)
|
|
Analysis Tools
