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| Nomenclature |
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Symbol:
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Tnfrsf13btm1Vmd
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Name:
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tumor necrosis factor receptor superfamily, member 13b;
targeted mutation 1, Vishva M Dixit
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MGI ID: |
MGI:2182823 |
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Synonyms: |
TACI- |
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Gene:
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Tnfrsf13b
Location:
Chr11:61126755-61149372 bp, + strand
Genetic Position: Chr11,
37.96 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:70172
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The region of the gene encoding the transmembrane domain and intracellular domain was replaced with a PGK-neo cassette via homologous recombination. The absence of gene expression in homozygous mutant animals was verified by Northern blot analysis of total spleen RNA. (J:70172)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tnfrsf13b Mutation:
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1 strain or line available |
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| References |
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Original: |
J:70172
Yan M et al.,
"Activation and accumulation of B cells in TACI-deficient mice."
Nat Immunol 2001 Jul;2(7):638-43
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All: |
3 reference(s)
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Analysis Tools
