|
|
| Nomenclature |
|
Symbol:
|
Ercc5tm1Shm
|
|
Name:
|
excision repair cross-complementing rodent repair deficiency, complementation group 5;
targeted mutation 1, Tadahiro Shiomi
|
|
MGI ID: |
MGI:2182793 |
|
Synonyms: |
Xpg-delta |
|
Gene:
|
Ercc5
Location:
Chr1:44147847-44181260 bp, + strand
Genetic Position: Chr1,
23.55 cM, cytoband B
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:53756
|
|
Parent Cell Line:
| D3 (ES Cell) |
|
Strain of Origin:
|
129S2/SvPas
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: Exon 3 was disrupted by the insertion of a neomycin selection cassette. Neither normal nor truncated transcript was detected by Northern blot analysis of total RNA obtained from newborn homozygous mutant mice. (J:53756)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:53756
Harada YN et al.,
"Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene."
Mol Cell Biol 1999 Mar;19(3):2366-72
|
|
All: |
3 reference(s)
|
|
Analysis Tools
