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| Nomenclature |
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Symbol:
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Efna5tm1Ddmo
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Name:
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ephrin A5;
targeted mutation 1, Dennis D M O'Leary
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MGI ID: |
MGI:2182573 |
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Synonyms: |
A5-, eA5KO, ephrin-A5- |
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Gene:
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Efna5
Location:
Chr17:62604184-62881317 bp, - strand
Genetic Position: Chr17,
32.57 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:45896
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette replaced sequence encoding amino acids 42 through 129 as well as a 5' splice acceptor. RT-PCR analysis showed an absence of transcript in homozygous mutant mice. (J:45896)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:45896
Frisen J et al.,
"Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system."
Neuron 1998 Feb;20(2):235-43
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All: |
30 reference(s)
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Analysis Tools
