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| Nomenclature |
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Symbol:
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Dmtf1tm1Cjs
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Name:
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cyclin D binding myb-like transcription factor 1;
targeted mutation 1, Charles J Sherr
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MGI ID: |
MGI:2182441 |
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Synonyms: |
DMP1- |
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Gene:
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Dmtf1
Location:
Chr5:9118801-9161749 bp, - strand
Genetic Position: Chr5,
3.69 cM, cytoband A2-A3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:63444
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: Exons encoding residues involved in DNA-binding were disrupted by the insertion of a 1.0kb neomycin selection cassette. Western blot analysis using antibodies raised against the carboxy terminal and the Myb-repeat domain showed an absence of encoded protein in homozygous mutant mice. (J:63444)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:63444
Inoue K et al.,
"Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis."
Genes Dev 2000 Jul 15;14(14):1797-809
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All: |
5 reference(s)
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Analysis Tools
