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| Nomenclature |
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Symbol:
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Nr4a1tm1Jmi
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Name:
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nuclear receptor subfamily 4, group A, member 1;
targeted mutation 1, Jeffrey Milbrandt
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MGI ID: |
MGI:2182325 |
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Synonyms: |
NGFI-B-, NGFI-B (-), Nur77- |
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Gene:
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Nr4a1
Location:
Chr15:101266846-101274792 bp, + strand
Genetic Position: Chr15,
56.64 cM, cytoband F
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:77686
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: Exon 2 was disrupted by the insertion of a neomycin resistance gene. Northern blot analysis of total thymic RNA showed an absence of transcript in homozygous mutant mice. (J:77686)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:77686
Lee SL et al.,
"Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)."
Science 1995 Jul 28;269(5223):532-5
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All: |
19 reference(s)
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Analysis Tools
