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| Nomenclature |
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Symbol:
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Tg(Ckmm-cre)5Khn
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Name:
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transgene insertion 5, C Ronald Kahn
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MGI ID: |
MGI:2182095 |
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Synonyms: |
Ckm-cre, Ckmm-cre, Ckmm-NLS-cre, CreMck, mckCRE, MCK-cre, MCKCre+, MCK-cre5, Tg(Ckm-cre)5Khn, Tg(Ckmm-cre)1Khn |
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Transgene:
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Tg(Ckmm-cre)5Khn
Location:
unknown
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Show the 1 image(s) involving this allele.
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: A 6.5 kb genomic DNA fragment of the Ckmm gene containing the promoter and enhancer 1, untranslated exon 1, 3kb of intron 1 including the enhancer 2 region, and the first 16 bp of exon 2 drives expression of a modified cre with an SV40 large T antigen nuclear localization signal. Expression is directed to the heart and skeletal muscle. (J:51266)
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Recombinase activity
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Activity:
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 Tissue activity of this recombinase allele
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Driver:
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Ckm
Summary of all recombinase alleles
driven by Ckm.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:51266
Bruning JC et al.,
"A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance."
Mol Cell 1998 Nov;2(5):559-69
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All: |
146 reference(s)
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Analysis Tools
