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| Nomenclature |
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Symbol:
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Slc2a4tm1Abel
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Name:
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solute carrier family 2 (facilitated glucose transporter), member 4;
targeted mutation 1, E Dale Abel
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MGI ID: |
MGI:2182083 |
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Synonyms: |
G4H - (cre lox), GLUT4 lox |
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Gene:
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Slc2a4
Location:
Chr11:69942539-69948188 bp, - strand
Genetic Position: Chr11,
42.93 cM, cytoband C-E1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:59054
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: LoxP sites were inserted flanking exon 10, which encodes the external and internal glucose binding sites. A neomycin selection cassette was also inserted downstream of the final coding exon. (J:59054)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc2a4 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:59054
Abel ED et al.,
"Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart."
J Clin Invest 1999 Dec;104(12):1703-14
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All: |
13 reference(s)
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Analysis Tools
