|
|
| Nomenclature |
|
Symbol:
|
Ins1tm1Jja
|
|
Name:
|
insulin I;
targeted mutation 1, Jacques Jami
|
|
MGI ID: |
MGI:2181877 |
|
Synonyms: |
Ins1- |
|
Gene:
|
Ins1
Location:
Chr19:52264323-52265456 bp, + strand
Genetic Position: Chr19,
46.76 cM
|
|
Growth retardation of Ins1tm1Jja/Ins1tm1Jja Ins2tm1Jja/Ins2tm1Jja mice
Show the 3 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:40377
|
|
Parent Cell Line:
| D3 (ES Cell) |
|
Strain of Origin:
|
129S2/SvPas
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: The majority of the coding region was replaced with a neomycin selection cassette. RT-PCR analysis showed an absence of transcript in homozygous mutant mice. (J:40377)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:40377
Duvillie B et al.,
"Phenotypic alterations in insulin-deficient mutant mice."
Proc Natl Acad Sci U S A 1997 May 13;94(10):5137-40
|
|
All: |
15 reference(s)
|
|
Analysis Tools
