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| Nomenclature |
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Symbol:
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Slc2a2tm1Thor
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Name:
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solute carrier family 2 (facilitated glucose transporter), member 2;
targeted mutation 1, Bernard Thorens
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MGI ID: |
MGI:2181752 |
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Synonyms: |
glut2- |
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Gene:
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Slc2a2
Location:
Chr3:28697903-28728356 bp, + strand
Genetic Position: Chr3,
12.19 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:43839
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Parent Cell Line:
| HM-1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd-Hprtb-m3
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 5, 6, and 7 were replaced by a neomycin selection cassette. Northern and Western blot analyses of liver tissue showed an absence of transcript and protein in homozygous mutant mice. (J:43839)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc2a2 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:43839
Guillam MT et al.,
"Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2 [see comments]"
Nat Genet 1997 Nov;17(3):327-30
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All: |
12 reference(s)
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Analysis Tools
