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| Nomenclature |
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Symbol:
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Gdf1tm1Sjl
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Name:
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growth differentiation factor 1;
targeted mutation 1, Se-Jin Lee
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MGI ID: |
MGI:2181719 |
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Synonyms: |
Gdf1- |
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Gene:
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Gdf1
Location:
Chr8:70329817-70331587 bp, + strand
Genetic Position: Chr8,
34.15 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:60755
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The gene was disrupted by replacement of exon 8 with a neomycin resistance cassette via homologous recombination. Homozygous mutant animals were identified by Southern blot analysis. (J:60755)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:60755
Rankin CT et al.,
"Regulation of left-right patterning in mice by growth/differentiation factor-1."
Nat Genet 2000 Mar;24(3):262-5
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All: |
4 reference(s)
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Analysis Tools
