|
|
| Nomenclature |
|
Symbol:
|
P2ry1tm1Gac
|
|
Name:
|
purinergic receptor P2Y, G-protein coupled 1;
targeted mutation 1, Christian Gachet
|
|
MGI ID: |
MGI:2181709 |
|
Synonyms: |
P2Y1- |
|
Gene:
|
P2ry1
Location:
Chr3:61002795-61008979 bp, + strand
Genetic Position: Chr3,
29.24 cM, cytoband E1
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:59055
|
|
Parent Cell Line:
| P1 (ES Cell) |
|
Strain of Origin:
|
129S2/SvPas
|
|
Mutation description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
The insertion of a neomycin cassette at nucleotide 3208 disrupted the coding region. (J:59055)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:59055
Leon C et al.,
"Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice [see comments]"
J Clin Invest 1999 Dec;104(12):1731-7
|
|
All: |
12 reference(s)
|
|