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P2ry1tm1Gac
Targeted Allele Detail

Nomenclature
Symbol: P2ry1tm1Gac
Name: purinergic receptor P2Y, G-protein coupled 1; targeted mutation 1, Christian Gachet
MGI ID: MGI:2181709
Synonyms: P2Y1-
Gene: P2ry1   Location: Chr3:61002795-61008979 bp, + strand    Genetic Position: Chr3, 29.24 cM, cytoband E1
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:59055
Parent Cell Line: P1 (ES Cell)
Strain of Origin: 129S2/SvPas
Mutation
description
Allele Type:   Targeted (knock-out)
Mutation:   Insertion
    The insertion of a neomycin cassette at nucleotide 3208 disrupted the coding region. (J:59055)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any P2ry1 Mutation: 4 strains or lines available
References
Original: J:59055 Leon C et al., "Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice [see comments]" J Clin Invest 1999 Dec;104(12):1731-7
All: 12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/22/2013
MGI 5.13
The Jackson Laboratory