|
|
| Nomenclature |
|
Symbol:
|
Rlbp1tm1Jsa
|
|
Name:
|
retinaldehyde binding protein 1;
targeted mutation 1, John C Saari
|
|
MGI ID: |
MGI:2181491 |
|
Synonyms: |
Rlbp1- |
|
Gene:
|
Rlbp1
Location:
Chr7:79374871-79387027 bp, - strand
Genetic Position: Chr7,
45.0 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:68444
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129X1/SvJ
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette into exon 3 via homologous recombination. Absence of gene expression in retinas of homozygous mutant mice was demonstrated by immunohistochemistry and Western blot analysis. (J:68444)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Rlbp1 Mutation:
|
5 strains or lines available |
|
| References |
|
Original: |
J:68444
Saari JC et al.,
"Visual cycle impairment in cellular retinaldehyde binding protein (CRALBP) knockout mice results in delayed dark adaptation."
Neuron 2001 Mar;29(3):739-48
|
|
All: |
1 reference(s)
|
|
Analysis Tools
