Ppp3cb<tm1Jmk> Targeted Allele Detail MGI Mouse (MGI:2181294)

Ppp3cb^tm1Jmk
Targeted Allele Detail

Nomenclature

Symbol:	Ppp3cb^tm1Jmk
Name:	protein phosphatase 3, catalytic subunit, beta isoform; targeted mutation 1, Jeffery D Molkentin
MGI ID:	MGI:2181294
Synonyms:	Abeta-, Cnab^-, CnAbeta-, CnAbeta KO
Gene:	Ppp3cb Location: Chr14:20499364-20546573 bp, - strand Genetic Position: Chr14, 11.53 cM, cytoband B

Cardiac histological analysis of wild type and Ppp3cb^tm1Jmk/Ppp3cb^tm1Jmk mice

Show the 1 image(s) involving this allele.

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:75775
Parent Cell Line:	KG-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Mutation
description

Allele Type:		Targeted (knock-out)
Mutations:		Insertion, Intragenic deletion
		Mutation details

Phenotypes

View phenotypes for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)

Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Ppp3cb Mutation:	20 strains or lines available

References

Original:	J:75775 Bueno OF et al., "Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice." Proc Natl Acad Sci U S A 2002 Apr 2;99(7):4586-91
All:	26 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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