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| Nomenclature |
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Symbol:
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Tnxbtm1Jbrs
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Name:
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tenascin XB;
targeted mutation 1, James Bristow
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MGI ID: |
MGI:2181283 |
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Synonyms: |
Tnxb- |
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Gene:
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Tnxb
Location:
Chr17:34670535-34719815 bp, + strand
Genetic Position: Chr17,
18.24 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:75812
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 2-6 were replaced with a PGK-neo-lacZ cassette via homologous recombination. The absence of mRNA and protein from skin of homozygous mutant animals was verified by Northern and Western blot analysis. (J:75812)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tnxb Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:75812
Mao JR et al.,
"Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition."
Nat Genet 2002 Apr;30(4):421-5
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All: |
2 reference(s)
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Analysis Tools
