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| Nomenclature |
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Symbol:
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Clutm1Jakh
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Name:
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clusterin;
targeted mutation 1, Judith A K Harmony
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MGI ID: |
MGI:2181011 |
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Synonyms: |
CLU- |
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Gene:
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Clu
Location:
Chr14:65968483-65981548 bp, + strand
Genetic Position: Chr14,
34.36 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:65660
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An HPRT cassette replaced exons 1 and 2. Normal transcript was undetectable in homozygous mutant tissue. Western blot analysis of plasma and liver extracts showed an absence of protein in homozygous mutant mice. (J:2892, J:65660, J:67960)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:65660
McLaughlin L et al.,
"Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis"
J Clin Invest 2000 Nov;106(9):1105-13
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All: |
22 reference(s)
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Analysis Tools
